产品货号：
Z16543
中文名称：
GCK抗体
英文名称：
Anti-GCK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GCK Antibody |
| 指标别名 | GCK;GK;GLK;Glucokinase;glucokinase (hexokinase 4);Hexokinase 4;Hexokinase D;Hexokinase type IV;HHF3;HK IV;HK4;HKIV;HXKP;MODY2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | GCK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Glucokinase recombinant protein (Position:Y234-T431). |
| 实际分子量 | 52KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Glucokinase(GCK) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate.Hexokinases phosphorylate glucose to produce glucose-6-phosphate,the first step in most glucose metabolism pathways.Alternative splicing of this gene results in three tissue-specific forms of glucokinase,one found in pancreatic islet beta cells and two found in liver.The protein localizes to the outer membrane of mitochondria.In contrast to other forms of hexokinase,this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant.Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM),maturity onset diabetes of the young,type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
| Uniprot ID | P35557 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 |
相关搜索：GCK抗体，GCK多抗，Anti-GCK Antibody